|
KMID : 0371320080750010027
|
|
Journal of the Korean Surgical Society
2008 Volume.75 No. 1 p.27 ~ p.31
|
|
|
Survival of Node-Positive Mucosal Gastric Carcinoma Patients
|
|
Cho Yong-Chul
Kim Ho-Goon
Jung Mi-Ran
Ryu Seong-Yeop
Park Young-Kyu
Kim Dong-Yi
Kim Young-Jin
|
|
|
Abstract
|
|
|
Purpose:The presence or absence of lymph node metastasis is significantly associated with the survival of patients with gastric carcinoma. We compared node-positive and node-negative mucosal gastric carcinoma patients to identify the clinicopathological characteristics of node-positive mucosal gastric carcinoma. We also evaluated the variables associated with lymph node metastasis and survival in this group of patients.
Method: Of the 580 mucosal gastric carcinoma patients, 32 (5.5%) were node-positive. A statistical analysis using the Cox model was performed to determine the factors that can predict the patients’ outcomes.
Results:The mean tumor size was significantly larger in the patients with node-positive mucosal gastric carcinoma than that in the node-negative patients (3.3 vs. 1.8 cm; P＜0.001). The overall survival rate was lower for the patients who were node-positive than for the patients who were node-negative (83.3% vs. 91.4%, respectively), but the difference was not significant (P＞0.05). Using the Cox proportional hazard regression model, tumor size was an independent statistically significant parameter associated with lymph node metastasis (risk ratio: 4.70, 95% confidence interval: 1.20 to 18.35; P＜0.05).
Conclusions:Tumor size is the most reliable predictor of lymph node metastasis for patients with node-positive mucosal gastric carcinoma. Nevertheless, a large tumor size is not associated with a poor outcome for patients with node-positive mucosal gastric carcinoma. The patients with node-positive mucosal gastric carcinoma showed good survival rates after undergoing gastrectomy and extensive node dissection.
|
|
|
KEYWORD
|
|
|
Gastric carcinoma, Node-positive, Mucosal, survival, Tumor size
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|